Understanding Ghrelin and Hunger Regulation

In the study of hunger and eating behaviors, it is essential to understand the various hormones involved in appetite regulation. One such hormone is ghrelin, which is often referred to as the 'hunger hormone.' Ghrelin is produced in the stomach and plays a significant role in signaling to the brain that the body requires food. Conversely, leptin, produced by fat cells, signals the brain to decrease appetite. Another critical factor in the regulation of hunger is the role of the hypothalamus. Which of the following statements accurately describes the relationship between ghrelin and hunger?