Adverse Effects of Anticoagulants: Apixaban

A nurse is preparing to educate a 70-year-old female patient who has been prescribed a new anticoagulant medication, apixaban, for the management of atrial fibrillation.

It is essential for the nurse to inform the patient about possible adverse effects associated with this medication.

Specifically, the nurse should emphasize the importance of recognizing signs of excessive bleeding, such as ___________ and ___________, which may indicate a serious complication.