Depression Treatment - Antidepressants

Biomedical therapies are a category of treatments for psychological disorders that primarily involve the use of medications and other biological interventions. These therapies aim to address the underlying biological causes of mental illnesses and often involve prescriptions and the application of physical techniques. One of the classical methods of biomedical therapy is the use of antidepressants. However, it's important to recognize that not all medications are effective for every individual, and understanding the specific mechanism of action for various classes of drugs is crucial for appropriate treatment.

In the context of treating depression, which of the following classes of medications works primarily by increasing the availability of neurotransmitters such as serotonin and norepinephrine in the synaptic cleft?