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Medical College Admission Test
Biological and Biochemical Foundations of Living Systems

Bioenergetics in Cellular Respiration

Hard Biochemistry Bioenergetics

In cellular respiration, the transformation of glucose into ATP involves a series of biochemical reactions that occur in different stages. These stages include glycolysis, the citric acid cycle, and oxidative phosphorylation. During glycolysis, glucose is broken down into pyruvate, producing a small yield of ATP and NADH. The citric acid cycle further processes pyruvate to produce additional NADH and FADH2, which are crucial for the next stage. In oxidative phosphorylation, the electrons from NADH and FADH2 are transferred through the electron transport chain (ETC), leading to the production of a large amount of ATP via chemiosmosis. A key component of the ETC is the proton gradient established across the mitochondrial membrane. Consider the energy transfer processes occurring in these stages.

Which of the following statements accurately describes a critical aspect of bioenergetics related to cellular respiration?

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