Calculation of Enthalpy Change in a Calorimetric Reaction

Consider the following thermodynamic scenario involving the calorimetry of a biochemical reaction. A researcher conducts an experiment to determine the enthalpy change (ΔH) for the reaction:

A + B → C + D

During the reaction, the researcher measures a temperature increase from 25.0 °C to 30.0 °C in a calorimeter containing 200 g of water. Assuming no heat is lost to the surroundings, calculate the enthalpy change (ΔH) for this reaction. The specific heat capacity of water is 4.18 J/g°C. What would be the value of ΔH in kilojoules per mole of reaction, assuming that the reaction produces 0.5 moles of products?