Compensation Mechanism for Rising Blood Glucose in Diabetics

The human body maintains homeostasis through the coordination of various systems, including the endocrine and nervous systems. A key aspect of maintaining stable internal conditions is the regulation of blood glucose levels. In individuals with diabetes, this regulation is impaired, leading to significant health issues. When blood glucose rises, a feedback loop is initiated, where insulin is secreted from the pancreas to facilitate the uptake of glucose by cells. This process is critical, given that glucose serves as a primary energy source for many cells in the body.

In a scenario where a patient lacks sufficient insulin production, what physiological response would you expect in order to compensate for rising blood glucose levels?