Effect of Saturated Fatty Acids on Membrane Fluidity

Very Hard Biochemistry Lipids And Membranes

In biological membranes, the phospholipid bilayer is fundamental to cellular structure and function. Each phospholipid molecule consists of a hydrophilic (water-attracting) phosphate head and two hydrophobic (water-repelling) fatty acid tails. This unique arrangement allows the bilayer to serve as a semi-permeable barrier, regulating the movement of substances in and out of the cell. Moreover, the fluidity and flexibility of the membrane are influenced by various factors, including temperature, the composition of fatty acids, and the presence of cholesterol. Consider a scenario where a cell is exposed to a high concentration of saturated fatty acids in its environment. Which of the following statements is most likely true regarding the impact of this exposure on the fluidity of the cell membrane?

The membrane fluidity will increase significantly as saturated fatty acids integrate into the bilayer.

The membrane fluidity will decrease due to the packing of saturated fatty acids, leading to increased rigidity.

The membrane fluidity will remain unchanged as the presence of saturated fatty acids does not affect the bilayer.

Cholesterol will compensate for the increased saturation, thus maintaining fluidity.

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