Effect of Temperature on Phospholipid Membrane Properties

Very Hard Biochemistry Lipids And Membranes

Phospholipids are vital components of cellular membranes, contributing to their structure and function. When subjected to varying temperatures, phospholipid bilayers demonstrate different phase behaviors that impact membrane fluidity.

Consider a situation where a membrane primarily composed of phospholipids with saturated fatty acid tails is cooled to below its transition temperature. Predict how the properties of this membrane would change and which of the following statements best describes the effect on membrane fluidity and permeability.

The membrane becomes more fluid and permeable due to increased kinetic energy.

The membrane transitions to a gel-like state, becoming less fluid and less permeable.

The membrane maintains fluidity but decreases in permeability due to hydrophobic interactions.

The membrane loses integrity, resulting in increased fluidity but decreased structural stability.

Hint

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