The human nervous system is a complex network responsible for various physiological functions, including the regulation of sensory and motor functions. It can be divided into the central nervous system (CNS) and the peripheral nervous system (PNS). Recent studies have illustrated the critical role of neurotransmitters, particularly glutamate and GABA, in synaptic transmission and neuroplasticity, which underlie learning and memory processes.
Glutamate is the primary excitatory neurotransmitter, facilitating fast synaptic transmission, while GABA serves as the main inhibitory neurotransmitter, contributing to the modulation of neuronal excitability. Any imbalance in the activity of these neurotransmitters can lead to various neuropsychiatric disorders, including anxiety, depression, and schizophrenia.
Consider a scenario where a researcher is investigating the interactions between glutamate and GABA in a model of chronic stress. This model demonstrates an alteration in the expression of key receptors for both neurotransmitters. What specific outcome would most likely result from a decrease in GABAergic activity during this study?