Effects of Sodium-Potassium Pump Inhibition on Neurons

Very Hard Biology Homeostasis And Transport

The biological concept of homeostasis refers to the ability of an organism to maintain stable internal conditions despite changes in external environments. One key aspect of homeostasis involves the regulation of ion concentrations across biological membranes. Neurons, in particular, utilize ion channels and pumps to maintain the necessary electrical gradients that allow for action potentials. For example, the sodium-potassium pump actively transports sodium ions out of the cell and potassium ions into the cell, maintaining an essential gradient for neuronal function.

Consider the following scenario: If a neuron is exposed to a substance that selectively inhibits the sodium-potassium pump, which of the following outcomes is most likely to occur in the neuron?

The neuron will become hyperpolarized, making it less likely to fire an action potential.

The neuron will exhibit an increase in resting membrane potential, becoming more positive.

The intracellular concentration of sodium will decrease significantly.

The action potential will be generated more easily due to increased sodium influx.

Hint

Submitted8.0K

Correct7.7K

% Correct97%