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Medical College Admission Test
Biological and Biochemical Foundations of Living Systems

Electrolyte Imbalances in Chronic Kidney Disease

Very Hard Biology Human Physiology

During a recent physiology class, students discussed the concept of homeostasis and the role of various organ systems in maintaining it. One student highlighted how the renal system works actively to ensure that electrolyte levels are balanced within the body. Additionally, they mentioned that the kidneys can modulate blood pressure through the renin-angiotensin-aldosterone system (RAAS). Another student pointed out that the cardiovascular system also plays a crucial role by regulating heart rate and vascular resistance.

As the discussion continued, they considered diseases associated with dysregulation of these systems. For instance, chronic kidney disease (CKD) is characterized by a gradual loss of kidney function. This loss disrupts the body's ability to regulate electrolytes, which can lead to various complications. They wondered which electrolyte imbalance is most commonly associated with CKD, particularly concerning potential adverse effects on cardiac function.

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