First Production of NADH in Citric Acid Cycle

Medium Biochemistry Metabolism

In human metabolism, the citric acid cycle (Krebs cycle) plays a crucial role in the oxidative degradation of carbohydrates, fats, and proteins. At which specific point in the citric acid cycle does the first production of NADH occur, and what is the primary substrate involved in this step?

At the formation of citrate from acetyl-CoA and oxaloacetate.

During the conversion of isocitrate to α-ketoglutarate.

During the transformation of succinyl-CoA to succinate.

At the conversion of fumarate to malate.

Hint

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