Function of DNA Polymerase I in DNA Replication

Very Hard Biochemistry Nucleic Acids And Dna Replication

During DNA replication, several enzymes and proteins play critical roles in ensuring the high fidelity of the process. DNA polymerases are the primary enzymes involved in synthesizing new DNA strands. They add nucleotides to a growing chain and have the ability to proofread the newly synthesized DNA. However, there are different DNA polymerases with varying functions. One type, DNA polymerase I, has a unique role in prokaryotic cells.

Which of the following statements correctly describes the unique function of DNA polymerase I during DNA replication in prokaryotes?

DNA polymerase I initiates DNA synthesis by adding the first nucleotide to the RNA primer.

DNA polymerase I has the primary role of extending the leading strand continuously.

DNA polymerase I replaces RNA primers with DNA after the Okazaki fragments are synthesized.

DNA polymerase I is primarily responsible for synthesizing the lagging strand in a continuous manner.

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