Implications of Mutant DNA Polymerase Delta on Replication

In the process of DNA replication, two main events occur: 1. The unwinding of the double helix structure of DNA, and 2. The synthesis of complementary strands from the originating template. This process is facilitated by a variety of enzymes including helicases, DNA polymerases, and ligases. Researchers have conducted extensive studies on how mutations in these enzymes can affect replication fidelity. A recent study indicates that a particular mutation in DNA polymerase delta (Pol ?), which is responsible for synthesizing the lagging strand, results in a decreased ability to proofread and correct errors during replication. This raises concerns about the overall stability of the organism's genome. Given this information, what implication does a malfunction of DNA polymerase delta have on DNA replication?