Key Enzyme in Acute Pancreatitis

A patient with a history of chronic alcoholism is admitted to the hospital for treatment of acute pancreatitis. During your assessment, you note the patient is exhibiting signs of abdominal pain, nausea, and tachycardia. You are aware that the pathophysiological mechanism underlying acute pancreatitis primarily involves the premature activation of digestive enzymes. In this context, one primary enzyme that, when activated, leads to the autodigestion of pancreatic tissue is ______.