In eukaryotic cells, gene expression is tightly regulated at multiple levels to ensure proper cellular function and development. One of the key mechanisms involved in the regulation of gene expression is RNA interference (RNAi), a biological process in which small RNA molecules inhibit gene expression, typically by causing the degradation of specific mRNA molecules. Recent studies have indicated that certain small interfering RNAs (siRNAs) can also lead to alterations in chromatin structure, thereby impacting gene transcription. Which of the following statements best describes a direct mechanistic role of siRNAs in regulating gene expression via RNAi?