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Medical College Admission Test
Biological and Biochemical Foundations of Living Systems

Mitochondrial Role in ATP Synthesis

Hard Biology Cellular Biology

During cellular respiration, glucose is metabolized to produce ATP, which serves as a primary energy carrier in cells. This process occurs in several metabolic pathways, including glycolysis, the citric acid cycle, and oxidative phosphorylation. The efficient production of ATP is essential for numerous cellular activities. Mitochondria, known as the powerhouse of the cell, play a crucial role in ATP synthesis through oxidative phosphorylation. Additionally, enzymes and electron carriers are instrumental in the process of transferring electrons and generating a proton gradient.

Regulation of cellular respiration is vital for maintaining homeostasis. Factors such as the availability of substrates (like glucose), the presence of oxygen, and the cell's energy demands can influence the rate of ATP production. Consider the following components involved in cellular respiration:

1. Glycolysis occurs in the cytoplasm and does not require oxygen.

2. The citric acid cycle occurs in the mitochondrial matrix and requires acetyl-CoA as a substrate.

3. Oxidative phosphorylation and the electron transport chain are located in the inner mitochondrial membrane.

Which of the following statements correctly characterizes a critical component of mitochondria regarding ATP synthesis?

Hint

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