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Medical College Admission Test
Chemical and Physical Foundations of Biological Systems

Nucleophilic Substitution vs. Elimination in 2-Bromobutane Reaction

Hard Organic Chemistry Nucleophilic Substitution And Elimination Reactions

In organic chemistry, nucleophilic substitution and elimination reactions are crucial for understanding molecular transformations. Consider the following scenario: You are tasked with determining the predominant reaction type that occurs when 2-bromobutane reacts with sodium hydroxide in ethanol at elevated temperatures. The structure of 2-bromobutane is as follows:

2-bromobutane structure

Given the basic nature of sodium hydroxide and the heat applied during the reaction, which of the following options represents the likely major product of this reaction?

Hint

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