Pathophysiological Changes in Liver Cirrhosis

Hard Physiological Adaptation Pathophysiology

A 45-year-old male patient is diagnosed with liver cirrhosis secondary to chronic alcohol use. As part of the nursing care plan, the nurse needs to understand the various pathophysiological changes that occur with this condition. Which of the following pathophysiological alterations should the nurse identify as being correct regarding liver cirrhosis? Select all that apply.

Select all that apply:

Portal hypertension resulting from increased resistance to blood flow in the portal venous system.

Decreased synthesis of clotting factors leading to increased risk of bleeding.

Hepatic dysfunction causing alterations in glucose metabolism, leading to hypoglycemia.

Accumulation of bile acids in the bloodstream resulting in itching and jaundice.

Increased production of urea due to enhanced protein metabolism.

Progressive fibrosis leading to loss of hepatic architecture and impaired liver function.

Hint

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