Pathophysiology of Multiple Organ Dysfunction Syndrome in Septic Shock

Very Hard Physiological Adaptation Pathophysiology

A patient presents to the emergency department with multiple organ dysfunction syndrome (MODS) following septic shock. During the assessment, several pathophysiological changes are noted. As the nurse, you must understand the underlying mechanisms contributing to these changes in order to provide optimal care.

Which of the following pathophysiological processes are likely involved in the development of MODS in this patient? Select all that apply.

Select all that apply:

Increased vascular permeability leading to edema.

Inhibition of normal apoptotic processes in lymphocytes.

Activation of the complement system.

Impaired mitochondrial function reducing ATP production.

Increased formation of nitric oxide causing vasodilation.

Release of pro-inflammatory cytokines causing systemic inflammation.

Hint

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