Pathophysiology of Myocardial Infarction

A 67-year-old male patient with a history of chronic hypertension and diabetes mellitus presents to the emergency department with complaints of severe chest pain radiating to his left arm. An electrocardiogram (ECG) reveals ST-segment elevation in leads II, III, and aVF. Lab tests show elevated troponin levels. Which pathophysiological change is most likely occurring in this patient?