In cellular respiration, glucose is metabolized to produce energy in the form of ATP. The glycolysis pathway is the first step in this process, occurring in the cytoplasm, where one molecule of glucose (a six-carbon compound) is split into two molecules of pyruvate (each containing three carbons). This pathway leads to a net production of ATP and NADH. In subsequent stages, such as the Krebs cycle and oxidative phosphorylation, pyruvate undergoes further oxidation to maximize ATP yield.
Which of the following accurately describes the regulation of glycolysis in response to energy needs within a cell?