Role of Primase in DNA Replication

Hard Biochemistry Nucleic Acids And Dna Replication

During DNA replication, the correct alignment of nucleotide bases is crucial for ensuring fidelity. The enzyme DNA polymerase adds nucleotides to the growing DNA strand. This process requires a template strand and must also involve the correct pairing of complementary nucleotides. Consider the role of primase in conjunction with DNA polymerase.

Which statement accurately describes the function of primase in DNA replication?

Primase synthesizes RNA primers which provide a 3'-OH group for DNA polymerase to extend.

Primase directly adds nucleotides to the leading strand to enhance its elongation.

Primase removes RNA primers after DNA synthesis is complete.

Primase serves as a proofreading mechanism to correct errors during nucleotide addition.

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