Thrombolytic Therapy Risks in Stroke Patients

Very Hard Physiological Adaptation Pathophysiology

A 72-year-old female with a history of hypertension and hyperlipidemia is brought to the emergency department after a sudden onset of right-sided weakness and slurred speech. A CT scan reveals an ischemic stroke in the left middle cerebral artery territory. The physician orders a thrombolytic therapy. However, the patient's recent history includes the use of anticoagulants for atrial fibrillation. As the nurse, you must evaluate the risks versus benefits of administering thrombolytics in this scenario. Which of the following statements best describes the potential pathophysiological implications of thrombolytic therapy in this patient?

Thrombolytic therapy is safe in patients taking anticoagulants, as it will enhance the effects of both medications.

Thrombolytic therapy may lead to increased risk of hemorrhagic conversion due to prior anticoagulant use.

Thrombolytic therapy is contraindicated for all patients with a history of atrial fibrillation regardless of anticoagulant use.

Thrombolytic therapy will have no significant impact on this patient's condition if anticoagulants were taken over 24 hours ago.

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