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Medical College Admission Test
Chemical and Physical Foundations of Biological Systems

Understanding Phospholipid Bilayer Fluidity

Medium Biochemistry Lipids And Membranes

Cell membranes are primarily composed of lipids, which play crucial roles in maintaining cellular structure and function. One important class of lipids is phospholipids, which are amphipathic molecules consisting of a hydrophilic 'head' group and two hydrophobic 'tails'. When placed in an aqueous environment, phospholipids spontaneously organize into bilayers, forming the foundation of cellular membranes.

Consider the structure and properties of phospholipids. The saturation of the fatty acid tails affects membrane fluidity significantly. Saturated fatty acids have no double bonds, which allows them to pack closely together, while unsaturated fatty acids contain one or more double bonds that introduce kinks in the chain, preventing tight packing.

Based on this information, which of the following statements about the properties of phospholipid bilayers is the most accurate?

Hint

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